A signaling cascade including ARID1A, GADD45B and DUSP1 induces apoptosis and affects the cell cycle of germ cell cancers after romidepsin treatment

In Western countries, the incidence of testicular germ cell cancers (GCC) is steadily rising over the last decades. Mostly, men between 20 and 40 years of age are affected. In general, patients suffering from GCCs are treated by orchiectomy and radio- or chemotherapy. Due to resistance mechanisms, i...

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Detalles Bibliográficos
Autores principales: Nettersheim, Daniel, Jostes, Sina, Fabry, Martin, Honecker, Friedemann, Schumacher, Valerie, Kirfel, Jutta, Kristiansen, Glen, Schorle, Hubert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342713/
https://www.ncbi.nlm.nih.gov/pubmed/27572311
http://dx.doi.org/10.18632/oncotarget.11647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342713/
https://www.ncbi.nlm.nih.gov/pubmed/27572311
http://dx.doi.org/10.18632/oncotarget.11647

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