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nc886, a non-coding RNA and suppressor of PKR, exerts an oncogenic function in thyroid cancer

nc886 is a recently identified cellular non-coding RNA and its depletion leads to acute cell death via PKR (Protein Kinase RNA-activated) activation. nc886 expression is increased in some malignancies, but silenced in others. However, the precise role of nc886/PKR is controversial: is it a tumor sup...

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Detalles Bibliográficos
Autores principales: Lee, Eun Kyung, Hong, Seung-Hyun, Shin, Sooyong, Lee, Hyun-Sung, Lee, Ju-Seog, Park, Eun Jung, Choi, Sun Shim, Min, Jae Woong, Park, Daeyoon, Hwang, Jung-Ah, Johnson, Betty H., Jeon, Sung Ho, Kim, In-Hoo, Lee, Yeon-Su, Lee, Yong Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342718/
https://www.ncbi.nlm.nih.gov/pubmed/27612419
http://dx.doi.org/10.18632/oncotarget.11852