MiR-139-5p reverses CD44(+)/CD133(+)-associated multidrug resistance by downregulating NOTCH1 in colorectal carcinoma cells

MiRNAs may promote or inhibit tumor recurrence and drug resistance. MiR-139-5p is reportedly downregulated in colorectal cancer patient samples, but it is unknown whether and how miR-139-5p regulates drug resistance. Cancer stem cells (CSCs) are postulated to be important promoters of multiple drug...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Ke, Shen, Ke, Liang, Xin, Li, Yueqi, Nagao, Norio, Li, Jiyu, Liu, Jianwen, Yin, Peihao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342727/
https://www.ncbi.nlm.nih.gov/pubmed/27738333
http://dx.doi.org/10.18632/oncotarget.12611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342727/
https://www.ncbi.nlm.nih.gov/pubmed/27738333
http://dx.doi.org/10.18632/oncotarget.12611

Ejemplares similares