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CD103+ intraepithelial T cells in high-grade serous ovarian cancer are phenotypically diverse TCRαβ+ CD8αβ+ T cells that can be targeted for cancer immunotherapy

CD103+ tumor-infiltrating lymphocytes (TIL) have been linked to specific epithelial infiltration and a prolonged survival in high-grade serous epithelial ovarian cancer (HGSC). However, whether these cells are induced as part of an ongoing anti-HGSC immune response or represent non-specifically expa...

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Detalles Bibliográficos
Autores principales: Komdeur, Fenne L., Wouters, Maartje C.A., Workel, Hagma H., Tijans, Aline M., Terwindt, Anouk L.J., Brunekreeft, Kim L., Plat, Annechien, Klip, Harry G., Eggink, Florine A., Leffers, Ninke, Helfrich, Wijnand, Samplonius, Douwe F., Bremer, Edwin, Wisman, G. Bea A., Daemen, Toos, Duiker, Evelien W., Hollema, Harry, Nijman, Hans W., de Bruyn, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342728/
https://www.ncbi.nlm.nih.gov/pubmed/27650547
http://dx.doi.org/10.18632/oncotarget.12077