Elevated level of acetylation of APE1 in tumor cells modulates DNA damage repair

Apurinic/apyrimidinic (AP) sites are frequently generated in the genome by spontaneous depurination/depyrimidination or after removal of oxidized/modified bases by DNA glycosylases during the base excision repair (BER) pathway. Unrepaired AP sites are mutagenic and block DNA replication and transcri...

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Detalles Bibliográficos
Autores principales: Sengupta, Shiladitya, Mantha, Anil K., Song, Heyu, Roychoudhury, Shrabasti, Nath, Somsubhra, Ray, Sutapa, Bhakat, Kishor K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342734/
https://www.ncbi.nlm.nih.gov/pubmed/27655688
http://dx.doi.org/10.18632/oncotarget.12113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342734/
https://www.ncbi.nlm.nih.gov/pubmed/27655688
http://dx.doi.org/10.18632/oncotarget.12113

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