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Somatic polyploidy is associated with the upregulation of c-MYC interacting genes and EMT-like signature

The dependence of cancer on overexpressed c-MYC and its predisposition for polyploidy represents a double puzzle. We address this conundrum by cross-species transcription analysis of c-MYC interacting genes in polyploid vs. diploid tissues and cells, including human vs. mouse heart, mouse vs. human...

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Detalles Bibliográficos
Autores principales: Vazquez-Martin, Alejandro, Anatskaya, Olga V., Giuliani, Alessandro, Erenpreisa, Jekaterina, Huang, Sui, Salmina, Kristine, Inashkina, Inna, Huna, Anda, Nikolsky, Nikolai N., Vinogradov, Alexander E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342737/
https://www.ncbi.nlm.nih.gov/pubmed/27655693
http://dx.doi.org/10.18632/oncotarget.12118