Induction of anti-EGFR immune response with mimotopes identified from a phage display peptide library by panitumumab

The epidermal growth factor receptor (EGFR) is overexpressed in several epithelial tumors. Anti-EGFR humanized monoclonal antibodies, cetuximab and panitumumab, in combination with chemotherapy have improved the prognosis for patients with wild-type RAS tumors. To identify mimotopes of EGFR and deve...

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Detalles Bibliográficos
Autores principales: Wang, Aidong, Cui, Ming, Qu, Hong, Di, Jiabo, Wang, Zaozao, Xing, Jiadi, Wu, Fan, Wu, Wei, Wang, Xicheng, Shen, Lin, Jiang, Beihai, Su, Xiangqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342741/
https://www.ncbi.nlm.nih.gov/pubmed/27659529
http://dx.doi.org/10.18632/oncotarget.12167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342741/
https://www.ncbi.nlm.nih.gov/pubmed/27659529
http://dx.doi.org/10.18632/oncotarget.12167

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