Focal adhesion molecule Kindlin-1 mediates activation of TGF-β signaling by interacting with TGF-βRI, SARA and Smad3 in colorectal cancer cells

Kindlin-1, an integrin-interacting protein, has been implicated in TGF-β/Smad3 signaling. However, the molecular mechanism underlying Kindlin-1 regulation of TGF-β/Smad3 signaling remains elusive. Here, we reported that Kindlin-1 is an important mediator of TGF-β/Smad3 signaling by showing that Kind...

Descripción completa

Detalles Bibliográficos
Autores principales: Kong, Jinfeng, Du, Juan, Wang, Yunling, Yang, Mingzi, Gao, Jianchao, Wei, Xiaofan, Fang, Weigang, Zhan, Jun, Zhang, Hongquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342809/
https://www.ncbi.nlm.nih.gov/pubmed/27776350
http://dx.doi.org/10.18632/oncotarget.12779

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342809/
https://www.ncbi.nlm.nih.gov/pubmed/27776350
http://dx.doi.org/10.18632/oncotarget.12779

Ejemplares similares