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Focal adhesion molecule Kindlin-1 mediates activation of TGF-β signaling by interacting with TGF-βRI, SARA and Smad3 in colorectal cancer cells

Kindlin-1, an integrin-interacting protein, has been implicated in TGF-β/Smad3 signaling. However, the molecular mechanism underlying Kindlin-1 regulation of TGF-β/Smad3 signaling remains elusive. Here, we reported that Kindlin-1 is an important mediator of TGF-β/Smad3 signaling by showing that Kind...

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Detalles Bibliográficos
Autores principales:	Kong, Jinfeng, Du, Juan, Wang, Yunling, Yang, Mingzi, Gao, Jianchao, Wei, Xiaofan, Fang, Weigang, Zhan, Jun, Zhang, Hongquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342809/ https://www.ncbi.nlm.nih.gov/pubmed/27776350 http://dx.doi.org/10.18632/oncotarget.12779

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