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Lipid droplet biology and evolution illuminated by the characterization of a novel perilipin in teleost fish

Perilipin (PLIN) proteins constitute an ancient family important in lipid droplet (LD) formation and triglyceride metabolism. We identified an additional PLIN clade (plin6) that is unique to teleosts and can be traced to the two whole genome duplications that occurred early in vertebrate evolution....

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Detalles Bibliográficos
Autores principales: Granneman, James G, Kimler, Vickie A, Zhang, Huamei, Ye, Xiangqun, Luo, Xixia, Postlethwait, John H, Thummel, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342826/
https://www.ncbi.nlm.nih.gov/pubmed/28244868
http://dx.doi.org/10.7554/eLife.21771