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Lipid droplet biology and evolution illuminated by the characterization of a novel perilipin in teleost fish
Perilipin (PLIN) proteins constitute an ancient family important in lipid droplet (LD) formation and triglyceride metabolism. We identified an additional PLIN clade (plin6) that is unique to teleosts and can be traced to the two whole genome duplications that occurred early in vertebrate evolution....
Autores principales: | Granneman, James G, Kimler, Vickie A, Zhang, Huamei, Ye, Xiangqun, Luo, Xixia, Postlethwait, John H, Thummel, Ryan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342826/ https://www.ncbi.nlm.nih.gov/pubmed/28244868 http://dx.doi.org/10.7554/eLife.21771 |
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