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Cerebrospinal Fluid Cortisol Mediates Brain-Derived Neurotrophic Factor Relationships to Mortality after Severe TBI: A Prospective Cohort Study

Distinct regulatory signaling mechanisms exist between cortisol and brain derived neurotrophic factor (BDNF) that may influence secondary injury cascades associated with traumatic brain injury (TBI) and predict outcome. We investigated concurrent CSF BDNF and cortisol relationships in 117 patients s...

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Detalles Bibliográficos
Autores principales: Munoz, Miranda J., Kumar, Raj G., Oh, Byung-Mo, Conley, Yvette P., Wang, Zhensheng, Failla, Michelle D., Wagner, Amy K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343043/
https://www.ncbi.nlm.nih.gov/pubmed/28337122
http://dx.doi.org/10.3389/fnmol.2017.00044