Cargando…

Intracellular calcium-dependent regulation of the sperm-specific calcium-activated potassium channel, hSlo3, by the BK(Ca) activator LDD175

Plasma membrane hyperpolarization associated with activation of Ca(2+)-activated K(+) channels plays an important role in sperm capacitation during fertilization. Although Slo3 (slowpoke homologue 3), together with the auxiliary γ2-subunit, LRRC52 (leucine-rich-repeat–containing 52), is known to med...

Descripción completa

Detalles Bibliográficos
Autores principales: Wijerathne, Tharaka Darshana, Kim, Jihyun, Yang, Dongki, Lee, Kyu Pil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343058/
https://www.ncbi.nlm.nih.gov/pubmed/28280418
http://dx.doi.org/10.4196/kjpp.2017.21.2.241