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Inhibition of K(+) outward currents by linopirdine in the cochlear outer hair cells of circling mice within the first postnatal week

Inhibition of K(+) outward currents by linopirdine in the outer hair cells (OHCs) of circling mice (homozygous (cir/cir) mice), an animal model for human deafness (DFNB6 type), was investigated using a whole cell patch clamp technique. Littermate heterozygous (+/cir) and ICR mice of the same age (po...

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Detalles Bibliográficos
Autores principales: Kang, Shin Wook, Ahn, Ji Woong, Ahn, Seung Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343059/
https://www.ncbi.nlm.nih.gov/pubmed/28280419
http://dx.doi.org/10.4196/kjpp.2017.21.2.251