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Gossypol has anti-cancer effects by dual-targeting MDM2 and VEGF in human breast cancer

BACKGROUND: Mouse double minute 2 (MDM2) and vascular endothelial growth factor (VEGF) are important molecules involved in tumor progression. We researched potential inhibitors that simultaneously target MDM2 and VEGF. In our recent study involving the performance of high-throughput screening with a...

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Detalles Bibliográficos
Autores principales: Xiong, Jing, Li, Jiansha, Yang, Qin, Wang, Jun, Su, Tiefen, Zhou, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343402/
https://www.ncbi.nlm.nih.gov/pubmed/28274247
http://dx.doi.org/10.1186/s13058-017-0818-5