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Gossypol has anti-cancer effects by dual-targeting MDM2 and VEGF in human breast cancer
BACKGROUND: Mouse double minute 2 (MDM2) and vascular endothelial growth factor (VEGF) are important molecules involved in tumor progression. We researched potential inhibitors that simultaneously target MDM2 and VEGF. In our recent study involving the performance of high-throughput screening with a...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343402/ https://www.ncbi.nlm.nih.gov/pubmed/28274247 http://dx.doi.org/10.1186/s13058-017-0818-5 |