B-Myb Induces APOBEC3B Expression Leading to Somatic Mutation in Multiple Cancers

The key signature of cancer genomes is the accumulation of DNA mutations, the most abundant of which is the cytosine-to-thymine (C-to-T) transition that results from cytosine deamination. Analysis of The Cancer Genome Atlas (TCGA) database has demonstrated that this transition is caused mainly by up...

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Detalles Bibliográficos
Autores principales: Chou, Wen-Cheng, Chen, Wei-Ting, Hsiung, Chia-Ni, Hu, Ling-Yueh, Yu, Jyh-Cherng, Hsu, Huan-Ming, Shen, Chen-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343453/
https://www.ncbi.nlm.nih.gov/pubmed/28276478
http://dx.doi.org/10.1038/srep44089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343453/
https://www.ncbi.nlm.nih.gov/pubmed/28276478
http://dx.doi.org/10.1038/srep44089

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