Flunarizine suppresses endothelial Angiopoietin-2 in a calcium - dependent fashion in sepsis

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to an infection leading to systemic inflammation and endothelial barrier breakdown. The vascular-destabilizing factor Angiopoietin-2 (Angpt-2) has been implicated in these processes in humans. Here we screened in a...

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Detalles Bibliográficos
Autores principales: Retzlaff, Jennifer, Thamm, Kristina, Ghosh, Chandra C., Ziegler, Wolfgang, Haller, Hermann, Parikh, Samir M., David, Sascha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343493/
https://www.ncbi.nlm.nih.gov/pubmed/28276491
http://dx.doi.org/10.1038/srep44113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343493/
https://www.ncbi.nlm.nih.gov/pubmed/28276491
http://dx.doi.org/10.1038/srep44113

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