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A microRNA-initiated DNAzyme motor operating in living cells

Synthetic DNA motors have great potential to mimic natural protein motors in cells but the operation of synthetic DNA motors in living cells remains challenging and has not been demonstrated. Here we report a DNAzyme motor that operates in living cells in response to a specific intracellular target....

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Detalles Bibliográficos
Autores principales: Peng, Hanyong, Li, Xing-Fang, Zhang, Hongquan, Le, X. Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343503/
https://www.ncbi.nlm.nih.gov/pubmed/28262725
http://dx.doi.org/10.1038/ncomms14378