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N-acetylcysteine downregulates phosphorylated p-38 expression but does not reverse the increased superoxide anion levels in the spinal cord of rats with neuropathic pain

We determined the effect of N-acetylcysteine (NAC) on the expression of the phosphorylated p38 (p-p38) protein and superoxide anion generation (SAG), two important players in the processing of neuropathic pain, in the lumbosacral spinal cord of rats with chronic constriction injury (CCI)-induced neu...

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Detalles Bibliográficos
Autores principales: Horst, A., de Souza, J.A., Santos, M.C.Q., Riffel, A.P.K., Kolberg, C., Ribeiro, M.F.M., de Fraga, L.S., Partata, W.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343557/
https://www.ncbi.nlm.nih.gov/pubmed/28225868
http://dx.doi.org/10.1590/1414-431X20165801