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The impact of the RBM4-initiated splicing cascade on modulating the carcinogenic signature of colorectal cancer cells

A growing body of studies has demonstrated that dysregulated splicing profiles constitute pivotal mechanisms for carcinogenesis. In this study, we identified discriminative splicing profiles of colorectal cancer (CRC) cells compared to adjacent normal tissues using deep RNA-sequencing (RNA-seq). The...

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Detalles Bibliográficos
Autores principales: Lin, Jung-Chun, Lee, Yuan-Chii, Liang, Yu-Chih, Fann, Yang C., Johnson, Kory R., Lin, Ying-Ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343574/
https://www.ncbi.nlm.nih.gov/pubmed/28276498
http://dx.doi.org/10.1038/srep44204