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Variability in statin-induced changes in gene expression profiles of pancreatic cancer

Statins, besides being powerful cholesterol-lowering drugs, also exert potent anti-proliferative activities. However, their anti-cancer efficacy differs among the individual statins. Thus, the aim of this study was to identify the biological pathways affected by individual statins in an in vitro mod...

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Detalles Bibliográficos
Autores principales: Gbelcová, Helena, Rimpelová, Silvie, Ruml, Tomáš, Fenclová, Marie, Kosek, Vítek, Hajšlová, Jana, Strnad, Hynek, Kolář, Michal, Vítek, Libor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343581/
https://www.ncbi.nlm.nih.gov/pubmed/28276528
http://dx.doi.org/10.1038/srep44219