Cargando…
Variability in statin-induced changes in gene expression profiles of pancreatic cancer
Statins, besides being powerful cholesterol-lowering drugs, also exert potent anti-proliferative activities. However, their anti-cancer efficacy differs among the individual statins. Thus, the aim of this study was to identify the biological pathways affected by individual statins in an in vitro mod...
Autores principales: | Gbelcová, Helena, Rimpelová, Silvie, Ruml, Tomáš, Fenclová, Marie, Kosek, Vítek, Hajšlová, Jana, Strnad, Hynek, Kolář, Michal, Vítek, Libor |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343581/ https://www.ncbi.nlm.nih.gov/pubmed/28276528 http://dx.doi.org/10.1038/srep44219 |
Ejemplares similares
-
Comparison of Transcriptomic Profiles of MiaPaCa-2 Pancreatic Cancer Cells Treated with Different Statins
por: Rimpelová, Silvie, et al.
Publicado: (2021) -
Isoprenoids responsible for protein prenylation modulate the biological effects of statins on pancreatic cancer cells
por: Gbelcová, Helena, et al.
Publicado: (2017) -
The effect of simvastatin on lipid droplets accumulation in human embryonic kidney cells and pancreatic cancer cells
por: Gbelcová, Helena, et al.
Publicado: (2013) -
Complex Evaluation of Antioxidant Capacity of Milk Thistle Dietary Supplements
por: Viktorova, Jitka, et al.
Publicado: (2019) -
Heme oxygenase is not involved in the anti-proliferative effects of statins on pancreatic cancer cells
por: Vanova, K., et al.
Publicado: (2016)