Predicting Protein Dynamics and Allostery Using Multi-Protein Atomic Distance Constraints

The related concepts of protein dynamics, conformational ensembles and allostery are often difficult to study with molecular dynamics (MD) due to the timescales involved. We present ExProSE (Exploration of Protein Structural Ensembles), a distance geometry-based method that generates an ensemble of...

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Detalles Bibliográficos
Autores principales: Greener, Joe G., Filippis, Ioannis, Sternberg, Michael J.E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2017
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343748/
https://www.ncbi.nlm.nih.gov/pubmed/28190781
http://dx.doi.org/10.1016/j.str.2017.01.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343748/
https://www.ncbi.nlm.nih.gov/pubmed/28190781
http://dx.doi.org/10.1016/j.str.2017.01.008

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