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Phenylarsine Oxide Can Induce the Arsenite-Resistance Mutant PML Protein Solubility Changes

Arsenic trioxide (As(2)O(3)) has recently become one of the most effective drugs for treatment of patient with acute promyelocytic leukemia (APL), and its molecular mechanism has also been largely investigated. However, it has been reported that As(2)O(3) resistant patients are frequently found in r...

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Detalles Bibliográficos
Autores principales: Jiang, Yu Han, Chen, Ye Jia, Wang, Chao, Lan, Yong Fei, Yang, Chang, Wang, Qian Qian, Hussain, Liaqat, Maimaitiying, Yasen, Islam, Khairul, Naranmandura, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343784/
https://www.ncbi.nlm.nih.gov/pubmed/28125064
http://dx.doi.org/10.3390/ijms18020247