Influence of Transgenic Metallothionein-1 on Gliosis, CA1 Neuronal Loss, and Brain Metal Levels of the Tg2576 Mouse Model of Alzheimer’s Disease

The mouse model of Alzheimer’s disease (AD), Tg2576 mice (APP), has provided valuable information, such as the role of the metallothionein (MT) family in their behavioral and amyloidosis phenotypes. In this study, we further characterize the role of MT-1 by crossing Mt1-overexpressing mice with Tg25...

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Detalles Bibliográficos
Autores principales: Comes, Gemma, Manso, Yasmina, Escrig, Anna, Fernandez-Gayol, Olaya, Sanchis, Paula, Molinero, Amalia, Giralt, Mercedes, Carrasco, Javier, Hidalgo, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343787/
https://www.ncbi.nlm.nih.gov/pubmed/28134760
http://dx.doi.org/10.3390/ijms18020251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343787/
https://www.ncbi.nlm.nih.gov/pubmed/28134760
http://dx.doi.org/10.3390/ijms18020251

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