Uridine Triphosphate Thio Analogues Inhibit Platelet P2Y(12) Receptor and Aggregation

Platelet P2Y(12) is an important adenosine diphosphate (ADP) receptor that is involved in agonist-induced platelet aggregation and is a valuable target for the development of anti-platelet drugs. Here we characterise the effects of thio analogues of uridine triphosphate (UTP) on ADP-induced platelet...

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Detalles Bibliográficos
Autores principales: Gündüz, Dursun, Tanislav, Christian, Sedding, Daniel, Parahuleva, Mariana, Santoso, Sentot, Troidl, Christian, Hamm, Christian W., Aslam, Muhammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343805/
https://www.ncbi.nlm.nih.gov/pubmed/28146050
http://dx.doi.org/10.3390/ijms18020269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343805/
https://www.ncbi.nlm.nih.gov/pubmed/28146050
http://dx.doi.org/10.3390/ijms18020269

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