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Acidosis Activates Endoplasmic Reticulum Stress Pathways through GPR4 in Human Vascular Endothelial Cells

Acidosis commonly exists in the tissue microenvironment of various pathophysiological conditions such as tumors, inflammation, ischemia, metabolic disease, and respiratory disease. For instance, the tumor microenvironment is characterized by acidosis and hypoxia due to tumor heterogeneity, aerobic g...

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Detalles Bibliográficos
Autores principales: Dong, Lixue, Krewson, Elizabeth A., Yang, Li V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343814/
https://www.ncbi.nlm.nih.gov/pubmed/28134810
http://dx.doi.org/10.3390/ijms18020278