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Decreased Expression of Vitamin D Receptor Affects an Immune Response in Primary Biliary Cholangitis via the VDR-miRNA155-SOCS1 Pathway

Primary biliary cholangitis (PBC) is an immune-mediated cholestatic disease. Vitamin D receptor (VDR)-dependent signaling constrains an inflammatory response by targeting the miRNA155-SOCS1 (suppressor of cytokine signaling 1) axis. The VDR-miRNA155-SOCS1 pathway was investigated in the context of t...

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Detalles Bibliográficos
Autores principales: Kempinska-Podhorodecka, Agnieszka, Milkiewicz, Malgorzata, Wasik, Urszula, Ligocka, Joanna, Zawadzki, Michał, Krawczyk, Marek, Milkiewicz, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343825/
https://www.ncbi.nlm.nih.gov/pubmed/28146070
http://dx.doi.org/10.3390/ijms18020289