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Sphingosine Kinase-1 Involves the Inhibitory Action of HIF-1α by Chlorogenic Acid in Hypoxic DU145 Cells

Hypoxia enhances cancer development in a solid tumor. Hypoxia-inducible factor-1 α (HIF-1α) is a transcription factor that is dominantly expressed under hypoxia in solid tumor cells and is a key factor that regulates tumor. HIF-1α regulates several target genes involved in many aspects of cancer pro...

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Detalles Bibliográficos
Autores principales: Lee, Myoung-Sun, Lee, Seon-Ok, Kim, Kyu-Ri, Lee, Hyo-Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343861/
https://www.ncbi.nlm.nih.gov/pubmed/28165392
http://dx.doi.org/10.3390/ijms18020325