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Increased Dicarbonyl Stress as a Novel Mechanism of Multi-Organ Failure in Critical Illness

Molecular pathological pathways leading to multi-organ failure in critical illness are progressively being unravelled. However, attempts to modulate these pathways have not yet improved the clinical outcome. Therefore, new targetable mechanisms should be investigated. We hypothesize that increased d...

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Detalles Bibliográficos
Autores principales: van Bussel, Bas C. T., van de Poll, Marcel C. G., Schalkwijk, Casper G., Bergmans, Dennis C. J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343881/
https://www.ncbi.nlm.nih.gov/pubmed/28178202
http://dx.doi.org/10.3390/ijms18020346