Cell Imaging Counting as a Novel Ex Vivo Approach for Investigating Drug-Induced Hepatotoxicity in Zebrafish Larvae

Drug-induced liver injury (DILI) is the most common reason for failures during the drug development process and for safety-related withdrawal of drugs from the pharmaceutical market. Therefore, having tools and techniques that can detect hepatotoxic properties in drug candidates at an early discover...

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Detalles Bibliográficos
Autores principales: Nguyen, Xuan-Bac, Kislyuk, Stanislav, Pham, Duc-Hung, Kecskés, Angela, Maes, Jan, Cabooter, Deirdre, Annaert, Pieter, De Witte, Peter, Ny, Annelii
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343891/
https://www.ncbi.nlm.nih.gov/pubmed/28208716
http://dx.doi.org/10.3390/ijms18020356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343891/
https://www.ncbi.nlm.nih.gov/pubmed/28208716
http://dx.doi.org/10.3390/ijms18020356

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