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Cell Imaging Counting as a Novel Ex Vivo Approach for Investigating Drug-Induced Hepatotoxicity in Zebrafish Larvae
Drug-induced liver injury (DILI) is the most common reason for failures during the drug development process and for safety-related withdrawal of drugs from the pharmaceutical market. Therefore, having tools and techniques that can detect hepatotoxic properties in drug candidates at an early discover...
Autores principales: | Nguyen, Xuan-Bac, Kislyuk, Stanislav, Pham, Duc-Hung, Kecskés, Angela, Maes, Jan, Cabooter, Deirdre, Annaert, Pieter, De Witte, Peter, Ny, Annelii |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343891/ https://www.ncbi.nlm.nih.gov/pubmed/28208716 http://dx.doi.org/10.3390/ijms18020356 |
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