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Recognition of Local DNA Structures by p53 Protein

p53 plays critical roles in regulating cell cycle, apoptosis, senescence and metabolism and is commonly mutated in human cancer. These roles are achieved by interaction with other proteins, but particularly by interaction with DNA. As a transcription factor, p53 is well known to bind consensus targe...

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Detalles Bibliográficos
Autores principales: Brázda, Václav, Coufal, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343910/
https://www.ncbi.nlm.nih.gov/pubmed/28208646
http://dx.doi.org/10.3390/ijms18020375