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Plasma Gelsolin Induced Glomerular Fibrosis via the TGF-β1/Smads Signal Transduction Pathway in IgA Nephropathy

Glomerular fibrosis has been shown to be closely related to the progression and prognosis of IgA nephropathy (IgAN). However, mechanism underlying IgAN glomerular fibrosis remains unclear. Recently, our study showed that plasma gelsolin (pGSN) was decreased in the serum of an IgAN mouse model and th...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Han, Changsong, Ye, Fei, He, Yan, Jin, Yinji, Wang, Tianzhen, Wu, Yiqi, Jiang, Yang, Zhang, Fengmin, Jin, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343925/
https://www.ncbi.nlm.nih.gov/pubmed/28208683
http://dx.doi.org/10.3390/ijms18020390