Essential Roles of E3 Ubiquitin Ligases in p53 Regulation

The ubiquitination pathway and proteasomal degradation machinery dominantly regulate p53 tumor suppressor protein stability, localization, and functions in both normal and cancerous cells. Selective E3 ubiquitin ligases dominantly regulate protein levels and activities of p53 in a large range of phy...

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Detalles Bibliográficos
Autores principales: Sane, Sanam, Rezvani, Khosrow
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343976/
https://www.ncbi.nlm.nih.gov/pubmed/28218667
http://dx.doi.org/10.3390/ijms18020442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343976/
https://www.ncbi.nlm.nih.gov/pubmed/28218667
http://dx.doi.org/10.3390/ijms18020442

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