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Essential Roles of E3 Ubiquitin Ligases in p53 Regulation
The ubiquitination pathway and proteasomal degradation machinery dominantly regulate p53 tumor suppressor protein stability, localization, and functions in both normal and cancerous cells. Selective E3 ubiquitin ligases dominantly regulate protein levels and activities of p53 in a large range of phy...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343976/ https://www.ncbi.nlm.nih.gov/pubmed/28218667 http://dx.doi.org/10.3390/ijms18020442 |