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Bioinformatics Approaches for Fetal DNA Fraction Estimation in Noninvasive Prenatal Testing
The discovery of cell-free fetal DNA molecules in plasma of pregnant women has created a paradigm shift in noninvasive prenatal testing (NIPT). Circulating cell-free DNA in maternal plasma has been increasingly recognized as an important proxy to detect fetal abnormalities in a noninvasive manner. A...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5343987/ https://www.ncbi.nlm.nih.gov/pubmed/28230760 http://dx.doi.org/10.3390/ijms18020453 |