Heat Shock Factor 1 Depletion Sensitizes A172 Glioblastoma Cells to Temozolomide via Suppression of Cancer Stem Cell-Like Properties

Heat shock factor 1 (HSF1), a transcription factor activated by various stressors, regulates proliferation and apoptosis by inducing expression of target genes, such as heat shock proteins and Bcl-2 (B-cell lymphoma 2) interacting cell death suppressor (BIS). HSF1 also directly interacts with BIS, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Im, Chang-Nim, Yun, Hye Hyeon, Lee, Jeong-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344000/
https://www.ncbi.nlm.nih.gov/pubmed/28241425
http://dx.doi.org/10.3390/ijms18020468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344000/
https://www.ncbi.nlm.nih.gov/pubmed/28241425
http://dx.doi.org/10.3390/ijms18020468

Ejemplares similares