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Regulation of DNA Damage Response by Estrogen Receptor β-Mediated Inhibition of Breast Cancer Associated Gene 2

Accumulating evidence suggests that ubiquitin E3 ligases are involved in cancer development as their mutations correlate with genomic instability and genetic susceptibility to cancer. Despite significant findings of cancer-driving mutations in the BRCA1 gene, estrogen receptor (ER)-positive breast c...

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Detalles Bibliográficos
Autores principales: Lee, Yuan-Hao, Sun, Youping, Gerweck, Leo E., Glickman, Randolph D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344223/
https://www.ncbi.nlm.nih.gov/pubmed/28536406
http://dx.doi.org/10.3390/biomedicines3020182