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Synthesis and Preliminary Biological Evaluations of Fluorescent or (149)Promethium Labeled Trastuzumab-Polyethylenimine
Background: Radioimmunotherapy utilize a targeting antibody coupled to a therapeutic isotope to target and treat a tumor or disease. In this study we examine the synthesis and cell binding of a polymer scaffold containing a radiotherapeutic isotope and a targeting antibody. Methods: The multistep sy...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344248/ https://www.ncbi.nlm.nih.gov/pubmed/28536369 http://dx.doi.org/10.3390/biomedicines4010001 |