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Synthesis and Preliminary Biological Evaluations of Fluorescent or (149)Promethium Labeled Trastuzumab-Polyethylenimine

Background: Radioimmunotherapy utilize a targeting antibody coupled to a therapeutic isotope to target and treat a tumor or disease. In this study we examine the synthesis and cell binding of a polymer scaffold containing a radiotherapeutic isotope and a targeting antibody. Methods: The multistep sy...

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Detalles Bibliográficos
Autores principales: Fitzsimmons, Jonathan, Nayak, Tapan, Cutler, Cathy, Atcher, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344248/
https://www.ncbi.nlm.nih.gov/pubmed/28536369
http://dx.doi.org/10.3390/biomedicines4010001