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Synthesis and Preliminary Biological Evaluations of Fluorescent or (149)Promethium Labeled Trastuzumab-Polyethylenimine

Background: Radioimmunotherapy utilize a targeting antibody coupled to a therapeutic isotope to target and treat a tumor or disease. In this study we examine the synthesis and cell binding of a polymer scaffold containing a radiotherapeutic isotope and a targeting antibody. Methods: The multistep sy...

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Detalles Bibliográficos
Autores principales:	Fitzsimmons, Jonathan, Nayak, Tapan, Cutler, Cathy, Atcher, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344248/ https://www.ncbi.nlm.nih.gov/pubmed/28536369 http://dx.doi.org/10.3390/biomedicines4010001

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