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Plant Toxin-Based Immunotoxins for Cancer Therapy: A Short Overview

Immunotoxins are chimeric proteins obtained by linking a toxin to either an intact antibody or an antibody fragment. Conjugation can be obtained by chemical or genetic engineering, where the latter yields recombinant conjugates. An essential requirement is that the target molecule recognized by the...

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Detalles Bibliográficos
Autores principales: Polito, Letizia, Djemil, Alice, Bortolotti, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344252/
https://www.ncbi.nlm.nih.gov/pubmed/28536379
http://dx.doi.org/10.3390/biomedicines4020012