Design, Synthesis and Biochemical Evaluation of Novel Selective Estrogen Receptor Ligand Conjugates Incorporating an Endoxifen-Combretastatin Hybrid Scaffold

Nuclear-receptors are often overexpressed in tumours and can thereby be used as targets when designing novel selective chemotherapeutic agents. To date, many conjugates incorporating an estrogen receptor (ER) ligand have been synthesised in order to direct chemical agents to tissue sites containing...

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Detalles Bibliográficos
Autores principales: Keely, Niall O., Carr, Miriam, Yassin, Bassem, Ana, Gloria, Lloyd, David G., Zisterer, Daniela, Meegan, Mary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344255/
https://www.ncbi.nlm.nih.gov/pubmed/28536383
http://dx.doi.org/10.3390/biomedicines4030015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344255/
https://www.ncbi.nlm.nih.gov/pubmed/28536383
http://dx.doi.org/10.3390/biomedicines4030015

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