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Epithelial-Mesenchymal Transition in Metastatic Cancer Cell Populations Affects Tumor Dormancy in a Simple Mathematical Model

Signaling from the c-Met receptor tyrosine kinase is associated with progression and metastasis of epithelial tumors. c-Met, the receptor for hepatocyte growth factor, triggers epithelial-mesenchymal transition (EMT) of cultured cells, which is thought to drive migration of tumor cells and confer on...

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Detalles Bibliográficos
Autores principales: MacLean, Adam L., Harrington, Heather A., Stumpf, Michael P. H., Hansen, Marc D. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344274/
https://www.ncbi.nlm.nih.gov/pubmed/28548077
http://dx.doi.org/10.3390/biomedicines2040384