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MLN64 induces mitochondrial dysfunction associated with increased mitochondrial cholesterol content

MLN64 is a late endosomal cholesterol-binding membrane protein that has been implicated in cholesterol transport from endosomal membranes to the plasma membrane and/or mitochondria, in toxin-induced resistance, and in mitochondrial dysfunction. Down-regulation of MLN64 in Niemann-Pick C1 deficient c...

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Detalles Bibliográficos
Autores principales: Balboa, Elisa, Castro, Juan, Pinochet, María-José, Cancino, Gonzalo I., Matías, Nuria, José Sáez, Pablo, Martínez, Alexis, Álvarez, Alejandra R., Garcia-Ruiz, Carmen, Fernandez-Checa, José C., Zanlungo, Silvana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344325/
https://www.ncbi.nlm.nih.gov/pubmed/28282615
http://dx.doi.org/10.1016/j.redox.2017.02.024