Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice

Pyrrolizidine alkaloids (PAs) are a group of compounds found in various plants and some of them are widely consumed in the world as herbal medicines and food supplements. PAs are potent hepatotoxins that cause irreversible liver injury in animals and humans. However, the mechanisms by which PAs indu...

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Detalles Bibliográficos
Autores principales: Yang, Xiao, Wang, Hua, Ni, Hong-Min, Xiong, Aizhen, Wang, Zhengtao, Sesaki, Hiromi, Ding, Wen-Xing, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344326/
https://www.ncbi.nlm.nih.gov/pubmed/28282614
http://dx.doi.org/10.1016/j.redox.2017.02.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344326/
https://www.ncbi.nlm.nih.gov/pubmed/28282614
http://dx.doi.org/10.1016/j.redox.2017.02.020

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