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Heterologous prime-boost vaccination with DNA and MVA vaccines, expressing HIV-1 subtype C mosaic Gag virus-like particles, is highly immunogenic in mice
In an effort to make affordable vaccines suitable for the regions most affected by HIV-1, we have constructed stable vaccines that express an HIV-1 subtype C mosaic Gag immunogen (BCG-Gag(M), MVA-Gag(M) and DNA-Gag(M)). Mosaic immunogens have been designed to address the tremendous diversity of this...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344398/ https://www.ncbi.nlm.nih.gov/pubmed/28278263 http://dx.doi.org/10.1371/journal.pone.0173352 |