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Heterologous prime-boost vaccination with DNA and MVA vaccines, expressing HIV-1 subtype C mosaic Gag virus-like particles, is highly immunogenic in mice

In an effort to make affordable vaccines suitable for the regions most affected by HIV-1, we have constructed stable vaccines that express an HIV-1 subtype C mosaic Gag immunogen (BCG-Gag(M), MVA-Gag(M) and DNA-Gag(M)). Mosaic immunogens have been designed to address the tremendous diversity of this...

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Detalles Bibliográficos
Autores principales:	Chapman, Ros, Jongwe, Tsungai Ivai, Douglass, Nicola, Chege, Gerald, Williamson, Anna-Lise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344398/ https://www.ncbi.nlm.nih.gov/pubmed/28278263 http://dx.doi.org/10.1371/journal.pone.0173352

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