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β(3)-Adrenoceptor activation upregulates apolipoprotein A-I expression in HepG2 cells, which might further promote cholesterol efflux from macrophage foam cells

OBJECTIVE: The aim of this study was to explore the effects of β(3)-adrenoceptor (β(3)-AR) activation on HepG2 cells and its influence on cholesterol efflux from macrophage foam cells. MATERIALS AND METHODS: HepG2 cells were cultured and treated with the β(3)-AR agonist, BRL37344, and antagonist, SR...

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Detalles Bibliográficos
Autores principales: Gao, Xia-qing, Li, Yan-fang, Jiang, Zhi-li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344441/
https://www.ncbi.nlm.nih.gov/pubmed/28424539
http://dx.doi.org/10.2147/DDDT.S130088